Expeditious Extraction of Histones from Limited Cells or Tissue Samples and Quantitative Top-Down Proteomic Analysis

Complete, excessive throughput evaluation of the plasma proteome has the potential to allow holistic evaluation of the well being state of a person. Based mostly on our personal expertise and the analysis of latest large-scale plasma mass spectrometry (MS) primarily based proteomic research, we recognized two excellent challenges: gradual and delicate nano-flow liquid chromatography (LC) and irreproducibility of identification of data-dependent acquisition (DDA). We decided an optimum answer decreasing these limitations with sturdy capillary-flow data-independent acquisition (DIA) MS. This platform can measure 31 plasma proteomes per day.

Utilizing this setup, we acquired a large-scale plasma examine of the eating regimen, weight problems and genes dietary (DiOGenes) comprising 1508 samples. Proving the robustness, the entire acquisition was achieved on a single analytical column. Completely, 565 proteins (459 recognized with two or extra peptide sequences) had been profiled with 74% information set completeness. On common 408 proteins (5246 peptides) had been recognized per acquisition (319 proteins in 90% of all acquisitions). The workflow reproducibility was assessed utilizing 34 high quality management swimming pools acquired at common intervals, leading to 92% information set completeness with CVs for protein measurements of 10.9%.

The profiles of 20 apolipoproteins may very well be profiled revealing distinct adjustments. The load loss and weight upkeep resulted in sustained results on low-grade irritation, in addition to steroid hormone and lipid metabolism, indicating useful results. Comparability to different large-scale plasma weight reduction research demonstrated excessive robustness and high quality of biomarker candidates recognized. Monitoring of nonenzymatic glycation indicated a delayed, slight discount of glycation within the weight upkeep section. Utilizing stable-isotope-references, we might instantly and completely quantify 60 proteins within the DIA. In conclusion, we current herein the primary large-scale plasma DIA examine and one of many largest scientific analysis proteomic research to this point. Utility of this quick and sturdy workflow has nice potential to advance biomarker discovery in plasma.

Blood-based protein biomarkers are more and more being explored as supplementary or environment friendly alternate options for population-based screening of colorectal most cancers (CRC). The target of the present examine was to check the diagnostic potential of proteins measured with completely different proteomic applied sciences. The concentrations of protein biomarkers had been measured utilizing proximity extension assays (PEAs), liquid chromatography/a number of response monitoring-mass spectrometry (LC/MRM-MS) and quantibody microarrays (QMAs) in plasma samples of 56 CRC sufferers and 99 individuals freed from neoplasms. In one other strategy, proteins had been measured in serum samples of 30 CRC circumstances and 30 individuals freed from neoplasm utilizing immunome full-length purposeful protein arrays (IpAs).

From all of the measurements, 9, 6, 35 and 14 protein biomarkers overlapped for comparative analysis of (a) PEA and LC/MRM-MS, (b) PEA and QMA, (c) PEA and IpA, and (d) LC/MRM-MS and IpA measurements, respectively. Correlation evaluation was carried out, together with calculation of the world below the curve (AUC) for assessing the diagnostic potential of every biomarker. DeLong’s take a look at was carried out to evaluate the variations in AUC.

AGAROSE MS, PCR SCREENING, MOLECULAR BIOLOGY GRADE, 100G/UNIT, 10 UNITS PER CASE
AGR-MS-1001	CORNING	1/pk	EUR 2038
Description: Bioscience Mol Bio; Agarose

LC-LC(+)-Biotin
abx184150-5g	Abbexa	5 g	EUR 996
Shipped within 1-2 weeks.

Human Osteonectin (ON) ELISA Kit
DLR-ON-Hu-48T	DL Develop	48T	EUR 479
Should the Human Osteonectin (ON) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A sandwich quantitative ELISA assay kit for detection of Human Osteonectin (ON) in samples from serum, plasma, tissue homogenates or other biological fluids.

Human Osteonectin (ON) ELISA Kit
DLR-ON-Hu-96T	DL Develop	96T	EUR 621
Should the Human Osteonectin (ON) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A sandwich quantitative ELISA assay kit for detection of Human Osteonectin (ON) in samples from serum, plasma, tissue homogenates or other biological fluids.

Mouse Osteonectin (ON) ELISA Kit
DLR-ON-Mu-48T	DL Develop	48T	EUR 489
Should the Mouse Osteonectin (ON) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Osteonectin (ON) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Mouse Osteonectin (ON) ELISA Kit
DLR-ON-Mu-96T	DL Develop	96T	EUR 635
Should the Mouse Osteonectin (ON) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Osteonectin (ON) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Rat Osteonectin (ON) ELISA Kit
DLR-ON-Ra-48T	DL Develop	48T	EUR 508
Should the Rat Osteonectin (ON) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A sandwich quantitative ELISA assay kit for detection of Rat Osteonectin (ON) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Rat Osteonectin (ON) ELISA Kit
DLR-ON-Ra-96T	DL Develop	96T	EUR 661
Should the Rat Osteonectin (ON) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A sandwich quantitative ELISA assay kit for detection of Rat Osteonectin (ON) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Human Osteonectin (ON) ELISA Kit
RD-ON-Hu-48Tests	Reddot Biotech	48 Tests	EUR 478

Human Osteonectin (ON) ELISA Kit
RD-ON-Hu-96Tests	Reddot Biotech	96 Tests	EUR 662

Mouse Osteonectin (ON) ELISA Kit
RD-ON-Mu-48Tests	Reddot Biotech	48 Tests	EUR 489

Mouse Osteonectin (ON) ELISA Kit
RD-ON-Mu-96Tests	Reddot Biotech	96 Tests	EUR 677

Rat Osteonectin (ON) ELISA Kit
RD-ON-Ra-48Tests	Reddot Biotech	48 Tests	EUR 511

Rat Osteonectin (ON) ELISA Kit
RD-ON-Ra-96Tests	Reddot Biotech	96 Tests	EUR 709

Human Osteonectin (ON) ELISA Kit
RDR-ON-Hu-48Tests	Reddot Biotech	48 Tests	EUR 500

Human Osteonectin (ON) ELISA Kit
RDR-ON-Hu-96Tests	Reddot Biotech	96 Tests	EUR 692

Mouse Osteonectin (ON) ELISA Kit
RDR-ON-Mu-48Tests	Reddot Biotech	48 Tests	EUR 511

Mouse Osteonectin (ON) ELISA Kit
RDR-ON-Mu-96Tests	Reddot Biotech	96 Tests	EUR 709

Rat Osteonectin (ON) ELISA Kit
RDR-ON-Ra-48Tests	Reddot Biotech	48 Tests	EUR 534

Rat Osteonectin (ON) ELISA Kit
RDR-ON-Ra-96Tests	Reddot Biotech	96 Tests	EUR 742

Trypsin, Recombinant, Proteomics grade
P1228-1000	Biovision		EUR 196

Trypsin, Recombinant, Proteomics grade
P1228-10000	Biovision		EUR 1224

Trypsin, Recombinant, Proteomics grade
P1228-5000	Biovision		EUR 615

HemoVoid™ Kit
HVK-05	Biotech Support Group	5 Preps	EUR 400
Description: Hemoglobin Removal Kit

HemoVoid™ Kit
HVK-10	Biotech Support Group	10 preps	EUR 587
Description: Hemoglobin Removal Kit

HemoVoid™ Kit
HVK-100	Biotech Support Group	100 preps	EUR 2983
Description: Hemoglobin Removal Kit

HemoVoid™ Kit
HVK-50	Biotech Support Group	50 preps	EUR 1846
Description: Hemoglobin Removal Kit

Biotin-LC-LC-NHS
2346-1000	Biovision		EUR 1675

Biotin-LC-LC-NHS
2346-250	Biovision		EUR 588

Biotin-LC-LC-NHS
2346-50	Biovision		EUR 196

Biotin-LC-LC-NHS
2346-5000	Biovision		Ask for price

HemoVoid Binding Buffer HVBB
HVBB-1000	Biotech Support Group	1000 mL	EUR 456
Description: HemoVoid™ Buffer

HemoVoid Binding Buffer HVBB
HVBB-500	Biotech Support Group	500 mL	EUR 245
Description: HemoVoid™ Buffer

HemoVoid Buffer Kit - 1000
HVBK-1000	Biotech Support Group	1000 mL	EUR 1166
Description: HemoVoid™ Buffer

HemoVoid Buffer Kit - 500
HVBK-500	Biotech Support Group	500 mL	EUR 615
Description: HemoVoid™ Buffer

HemoVoid Elution Buffer HVEB
HVEB-1000	Biotech Support Group	1000 mL	EUR 456
Description: HemoVoid™ Buffer

HemoVoid Elution Buffer HVEB
HVEB-500	Biotech Support Group	500 mL	EUR 245
Description: HemoVoid™ Buffer

HemoVoid Wash Buffer HVWB
HVWB-1000	Biotech Support Group	1000 mL	EUR 456
Description: HemoVoid™ Buffer

HemoVoid Wash Buffer HVWB
HVWB-500	Biotech Support Group	500 mL	EUR 245
Description: HemoVoid™ Buffer

Biotinylated Bovine Serum Albumin (Biotin-LC-BSA) (3 biotin/BSA)
7097-25	Biovision		EUR 222

Biotinylated Bovine Serum Albumin (Biotin-LC-BSA) (3 biotin/BSA)
7097-5	Biovision		EUR 115

Biotinylated Bovine Serum Albumin (Biotin-LC-BSA) (5 biotin/BSA)
7098-25	Biovision		EUR 233

Biotinylated Bovine Serum Albumin (Biotin-LC-BSA) (5 biotin/BSA)
7098-5	Biovision		EUR 120

Biotinylated Bovine Serum Albumin (Biotin-LC-BSA) (12 biotin/BSA)
7099-25	Biovision		EUR 244

Biotinylated Bovine Serum Albumin (Biotin-LC-BSA) (12 biotin/BSA)
7099-5	Biovision		EUR 131

101Bio Protein Solubilization Reagent for MS
P5W11	101Bio	NULL	EUR 0

Micro Bead Sterlizer
B1201-E	BenchMark	1 PC	EUR 542.7
To order instruments in 115V / US plug please delete the 'E' off the order code.European 2 pin plugs will be supplied as standard, please request UK if required.

Micro Bead Sterlizer
B1202-E	BenchMark	1 PC	EUR 84.14
To order instruments in 115V / US plug please delete the 'E' off the order code.European 2 pin plugs will be supplied as standard, please request UK if required.

MS-1020
GL5031-1MG	Glentham Life Sciences	1 mg	EUR 160

MS 275
abx076834-1mg	Abbexa	1 mg	EUR 314
Shipped within 5-12 working days.

Ms-275
20-abx182582	Abbexa	EUR 509.00 EUR 300.00	100 mg 10 mg
Shipped within 1-2 weeks.

MS-1020
1911-1	Biovision		EUR 164

Refill Glass Beads
B1201-BEAD	BenchMark	1 PC	EUR 117.78
To order instruments in 115V / US plug please delete the 'E' off the order code.European 2 pin plugs will be supplied as standard, please request UK if required.

LC-Protein Kinase G Substrate; LC-Gsubtide (Biotin)
20-abx265657	Abbexa	EUR 467.00 EUR 773.00 EUR 356.00	10 mg 25 mg 5 mg
Shipped within 5-10 working days.

ELISA kit for Human MS (Melatonin Sulfate)
E-EL-H1726	Elabscience Biotech	1 plate of 96 wells	EUR 534
Gentaur's MS ELISA kit utilizes the Competitive-ELISA principle. The micro ELISA plate provided in this kit has been pre-coated with Human MS. During the reaction, Human MS in the sample or standard competes with a fixed amount of Human MS on the sol Show more
Description: A competitive ELISA kit for quantitative measurement of Human MS (Melatonin Sulfate) in samples from Serum, Plasma, Cell supernatant

ELISA kit for Human Melatonin sulfate (MS)
KTE61523-48T	Abbkine	48T	EUR 354
Description: Quantitative sandwich ELISA for measuring Human Melatonin sulfate (MS) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Human Melatonin sulfate (MS)
KTE61523-5platesof96wells	Abbkine	5 plates of 96 wells	EUR 2252
Description: Quantitative sandwich ELISA for measuring Human Melatonin sulfate (MS) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Human Melatonin sulfate (MS)
KTE61523-96T	Abbkine	96T	EUR 572
Description: Quantitative sandwich ELISA for measuring Human Melatonin sulfate (MS) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

sulfo-LC-SPDP
ADC-L-133	Creative Biolabs	unit	Ask for price

Biotin LC hydrazide
HY-101885	MedChemExpress	5mg	EUR 119

CD224 LC Antibody
20-abx121054	Abbexa	EUR 300.00 EUR 439.00 EUR 189.00	100 ul 200 ul 30 ul
Shipped within 5-10 working days.

Enteropeptidase LC Antibody
20-abx121089	Abbexa	EUR 300.00 EUR 439.00 EUR 189.00	100 ul 200 ul 30 ul
Shipped within 5-10 working days.

MASP1 LC Antibody
20-abx121154	Abbexa	EUR 300.00 EUR 439.00 EUR 189.00	100 ul 200 ul 30 ul
Shipped within 5-10 working days.

Myeloperoxidase LC Antibody
20-abx121172	Abbexa	EUR 300.00 EUR 439.00 EUR 189.00	100 ul 200 ul 30 ul
Shipped within 5-10 working days.

CD49e LC Antibody
20-abx009097	Abbexa	EUR 300.00 EUR 439.00 EUR 189.00	100 ul 200 ul 30 ul
Shipped within 5-10 working days.

CD49f LC Antibody
20-abx009102	Abbexa	EUR 300.00 EUR 439.00 EUR 189.00	100 ul 200 ul 30 ul
Shipped within 5-10 working days.

sulfo-LC-(+)-Biotin
20-abx185570	Abbexa	EUR 370.00 EUR 1261.00 EUR 578.00	100 mg 1 g 250 mg
Shipped within 1-2 weeks.

LC-(+)-Biotin hydrazide
abx185659-1g	Abbexa	1 g	EUR 648
Shipped within 1-2 weeks.

LC-NHS-(+)-Biotin
20-abx185861	Abbexa	EUR 634.00 EUR 398.00	1 g 250 mg
Shipped within 1-2 weeks.

CD49f LC antibody
70R-49925	Fitzgerald	100 ul	EUR 244
Description: Purified Polyclonal CD49f LC antibody

CD49e LC antibody
70R-49932	Fitzgerald	100 ul	EUR 244
Description: Purified Polyclonal CD49e LC antibody

NHS-LC-Biotin
A8004-100	ApexBio	100 mg	EUR 119
Description: NHS-LC-biotin (succinimidyl-6-(biotinamindo)hexanoate), also known as NHS-X-biotin is a derivative of D-biotin, a amine-reactive biotinylation agent, that contains a spacer arm off the valeric acid side chain of D-biotin with an NHS ester group at its end.

NHS-LC-Biotin
A8004-1000	ApexBio	1 g	EUR 548
Description: NHS-LC-biotin (succinimidyl-6-(biotinamindo)hexanoate), also known as NHS-X-biotin is a derivative of D-biotin, a amine-reactive biotinylation agent, that contains a spacer arm off the valeric acid side chain of D-biotin with an NHS ester group at its end.

Iodoacetyl-LC-Biotin
A8009-100	ApexBio	100 mg	EUR 264
Description: Iodoacetyl-LC-Biotin (N-iodoacetyl-N-biotinylhexylenediamine), a sulfhydryl-reactive biotinylation agent, is a water-insoluble reagent that requires the dissolution of suitable solvents, including dimethyl sulfoxide (DMSO) and dimethylformamide (DMF).

Biotin-LC-Kemptide
5-00800	CHI Scientific	4 x 1mg	Ask for price

Kininogen LC antibody
23031-100ul	SAB	100ul	EUR 390

Sulfo-LC-SPDP
2325-250	Biovision		EUR 1567

Sulfo-LC-SPDP
2325-50	Biovision		EUR 436

Biotin-LC-NHS
2345-1000	Biovision		EUR 1001

Biotin-LC-NHS
2345-250	Biovision		EUR 419

Biotin-LC-NHS
2345-50	Biovision		EUR 142

pPINK- LC Plasmid
PVT4035	Lifescience Market	2 ug	EUR 325

HemoVoid™ - Blood Card Reagent Kit
HVBC-10	Biotech Support Group	10 preps	EUR 552
Description: Hemoglobin Removal Kit

HemoVoid™ - Blood Card Reagent Kit
HVBC-100	Biotech Support Group	100 preps	EUR 2937
Description: Hemoglobin Removal Kit

HemoVoid™ - Blood Card Reagent Kit
HVBC-50	Biotech Support Group	50 preps	EUR 1770
Description: Hemoglobin Removal Kit

BrightGreen miRNA qPCR MasterMix-No Dye
MasterMix-mS	ABM	4 x 1.25 ml for 500 reactions	EUR 151

Bangs Lab Bead Solution
SOLN1-1000	Bangs Laboratories	1000 ML	EUR 155.06
Description: Bangs Lab Bead Solution is ready-to-use solution and is suitable for dilution and/or storage of plain, dyed, or functionalized polymer microspheres

Bangs Lab Bead Solution
SOLN1-2000	Bangs Laboratories	2000 ML	EUR 212.7
Description: Bangs Lab Bead Solution is ready-to-use solution and is suitable for dilution and/or storage of plain, dyed, or functionalized polymer microspheres

Bangs Lab Bead Solution
SOLN1-500	Bangs Laboratories	500 ML	EUR 98.51
Description: Bangs Lab Bead Solution is ready-to-use solution and is suitable for dilution and/or storage of plain, dyed, or functionalized polymer microspheres

uv lamp 2x15w, 254/365nm
VL215-LC	Consort	ea	EUR 817

uv lamp 2x6w, 254/365nm
VL6-LC	Consort	ea	EUR 538

darkroom 254/365nm
VLCN15-LC	Consort	ea	EUR 1535

ELISA kit for Mouse ON (Osteonectin)
E-EL-M0867	Elabscience Biotech	1 plate of 96 wells	EUR 534
Gentaur's ON ELISA kit utilizes the Sandwich-ELISA principle. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to Mouse ON. Standards or samples are added to the micro ELISA plate wells and combined with the sp Show more
Description: A sandwich ELISA kit for quantitative measurement of Mouse ON (Osteonectin) in samples from Serum, Plasma, Cell supernatant

ELISA kit for Human ON (Osteonectin)
ELK1682	ELK Biotech	1 plate of 96 wells	EUR 432
The microtiter plate provided in this kit has been pre-coated with an antibody specific to Osteonectin (ON). Standards or samples are then added to the appropriate microtiter plate wells with a biotin-conjugated antibody specific to Osteonectin (ON). Show more
Description: A sandwich ELISA kit for detection of Osteonectin from Human in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

ELISA kit for Rat ON (Osteonectin)
ELK1683	ELK Biotech	1 plate of 96 wells	EUR 432
The microtiter plate provided in this kit has been pre-coated with an antibody specific to Osteonectin (ON). Standards or samples are then added to the appropriate microtiter plate wells with a biotin-conjugated antibody specific to Osteonectin (ON). Show more
Description: A sandwich ELISA kit for detection of Osteonectin from Rat in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

ELISA kit for Mouse ON (Osteonectin)
ELK1684	ELK Biotech	1 plate of 96 wells	EUR 432
The microtiter plate provided in this kit has been pre-coated with an antibody specific to Osteonectin (ON). Standards or samples are then added to the appropriate microtiter plate wells with a biotin-conjugated antibody specific to Osteonectin (ON). Show more
Description: A sandwich ELISA kit for detection of Osteonectin from Mouse in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

CLIA kit for Human ON (Osteonectin)
E-CL-H0889	Elabscience Biotech	1 plate of 96 wells	EUR 584
Gentaur's ON CLIA kit utilizes the Sandwich- CLIA principle. The micro CLIA plate provided in this kit has been pre-coated with an antibody specific to Human ON . Standards or samples are added to the micro CLIA plate wells and combined with the spec Show more
Description: A sandwich CLIA kit for quantitative measurement of Human ON (Osteonectin) in samples from Serum, Plasma, Cell supernatant

CLIA kit for Mouse ON (Osteonectin)
E-CL-M0530	Elabscience Biotech	1 plate of 96 wells	EUR 584
Gentaur's ON CLIA kit utilizes the Sandwich- CLIA principle. The micro CLIA plate provided in this kit has been pre-coated with an antibody specific to Mouse ON . Standards or samples are added to the micro CLIA plate wells and combined with the spec Show more
Description: A sandwich CLIA kit for quantitative measurement of Mouse ON (Osteonectin) in samples from Serum, Plasma, Cell supernatant

ELISA kit for Rat ON (Osteonectin)
E-EL-R0701	Elabscience Biotech	1 plate of 96 wells	EUR 534
Gentaur's ON ELISA kit utilizes the Sandwich-ELISA principle. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to Rat ON. Standards or samples are added to the micro ELISA plate wells and combined with the spec Show more
Description: A sandwich ELISA kit for quantitative measurement of Rat ON (Osteonectin) in samples from Serum, Plasma, Cell supernatant

CLIA kit for Rat ON (Osteonectin)
E-CL-R0498	Elabscience Biotech	1 plate of 96 wells	EUR 584
Gentaur's ON CLIA kit utilizes the Sandwich- CLIA principle. The micro CLIA plate provided in this kit has been pre-coated with an antibody specific to Rat ON . Standards or samples are added to the micro CLIA plate wells and combined with the specif Show more
Description: A sandwich CLIA kit for quantitative measurement of Rat ON (Osteonectin) in samples from Serum, Plasma, Cell supernatant

ELISA kit for Human ON (Osteonectin)
E-EL-H1351	Elabscience Biotech	1 plate of 96 wells	EUR 534
Gentaur's ON ELISA kit utilizes the Sandwich-ELISA principle. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to Human ON. Standards or samples are added to the micro ELISA plate wells and combined with the sp Show more
Description: A sandwich ELISA kit for quantitative measurement of Human ON (Osteonectin) in samples from Serum, Plasma, Cell supernatant

ELISA kit for Human Osteonectin (ON)
KTE60336-48T	Abbkine	48T	EUR 354
Osteonectin is a glycoprotein in the bone that binds calcium. It is secreted by osteoblasts during bone formation, initiating mineralization and promoting mineral crystal formation. Osteonectin also shows affinity for collagen in addition to bone min Show more
Description: Quantitative sandwich ELISA for measuring Human Osteonectin (ON) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Human Osteonectin (ON)
KTE60336-5platesof96wells	Abbkine	5 plates of 96 wells	EUR 2252
Osteonectin is a glycoprotein in the bone that binds calcium. It is secreted by osteoblasts during bone formation, initiating mineralization and promoting mineral crystal formation. Osteonectin also shows affinity for collagen in addition to bone min Show more
Description: Quantitative sandwich ELISA for measuring Human Osteonectin (ON) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Human Osteonectin (ON)
KTE60336-96T	Abbkine	96T	EUR 572
Osteonectin is a glycoprotein in the bone that binds calcium. It is secreted by osteoblasts during bone formation, initiating mineralization and promoting mineral crystal formation. Osteonectin also shows affinity for collagen in addition to bone min Show more
Description: Quantitative sandwich ELISA for measuring Human Osteonectin (ON) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

MS 245 oxalate
B5540-10	ApexBio	10 mg	EUR 292

MS 245 oxalate
B5540-5	ApexBio	5 mg	EUR 210

MS-275 (Entinostat)
E1KS1053	EnoGene	25 mg	EUR 247

Methyl-PEG3-MS
abx186609-250mg	Abbexa	250 mg	EUR 439
Shipped within 1-2 weeks.

Biotin-LC-Protein Kinase G Substrate; Biotin-LC-G-Subtide
5-00802	CHI Scientific	4 x 5mg	Ask for price

Polyclonal CD49e LC Antibody
APR05533G	Leading Biology	0.1ml	EUR 484
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human CD49e LC . This antibody is tested and proven to work in the following applications:

Cathepsin C LC Antibody
20-abx121043	Abbexa	EUR 300.00 EUR 439.00 EUR 189.00	100 ul 200 ul 30 ul
Shipped within 5-10 working days.

CD41 LC 1 Antibody
20-abx121061	Abbexa	EUR 300.00 EUR 439.00 EUR 189.00	100 ul 200 ul 30 ul
Shipped within 5-10 working days.

Factor IX LC Antibody
20-abx121094	Abbexa	EUR 300.00 EUR 439.00 EUR 189.00	100 ul 200 ul 30 ul
Shipped within 5-10 working days.

Factor XI LC Antibody
20-abx121097	Abbexa	EUR 300.00 EUR 439.00 EUR 189.00	100 ul 200 ul 30 ul
Shipped within 5-10 working days.

CD224 LC Blocking Peptide
20-abx161054	Abbexa	EUR 272.00 EUR 411.00	1 mg 5 mg
Shipped within 5-10 working days.

Enteropeptidase LC Blocking Peptide
20-abx161089	Abbexa	EUR 272.00 EUR 411.00	1 mg 5 mg
Shipped within 5-10 working days.

MASP1 LC Blocking Peptide
20-abx161154	Abbexa	EUR 272.00 EUR 411.00	1 mg 5 mg
Shipped within 5-10 working days.

Myeloperoxidase LC Blocking Peptide
20-abx161172	Abbexa	EUR 272.00 EUR 411.00	1 mg 5 mg
Shipped within 5-10 working days.

CD49f LC Blocking Peptide
20-abx062800	Abbexa	EUR 272.00 EUR 411.00	1 mg 5 mg
Shipped within 5-10 working days.

CD49e LC Blocking Peptide
20-abx062807	Abbexa	EUR 272.00 EUR 411.00	1 mg 5 mg
Shipped within 5-10 working days.

Cathepsin D LC Antibody
20-abx009376	Abbexa	EUR 300.00 EUR 439.00 EUR 189.00	100 ul 200 ul 30 ul
Shipped within 5-10 working days.

Analysis of the 9 biomarkers measured with PEA and LC/MRM-MS displayed correlation coefficients >+0.6, related AUCs and DeLong’s p-values indicating no variations in AUCs for biomarkers like insulin-like development issue binding protein 2 (IGFBP2), matrix metalloproteinase 9 (MMP9) and serum paraoxonase lactonase 3 (PON3). Evaluating six proteins measured with PEA and QMA confirmed good correlation and related diagnostic efficiency for just one protein, development differentiation issue 15 (GDF15).