Spirocerca lupi Proteomics and Its Role in Cancer Development: An Overview of Spirocercosis-Induced Sarcomas and Revision of Helminth-Induced Carcinomas

Spirocerca lupi Proteomics and Its Role in Cancer Development: An Overview of Spirocercosis-Induced Sarcomas and Revision of Helminth-Induced Carcinomas

Spirocerca lupi is a parasitic nematode of canids that induces a myriad of medical manifestations in its host and, in 25% of infections, results in the formation of sarcomas. The outline of the protein composition of the excretory and secretory merchandise (Sl-ESP) of S. lupi has make clear its doable interactions with the host atmosphere, together with migration throughout the host and mechanisms of immunomodulation. Regardless of this, the method by which S. lupi induces most cancers within the canine stays poorly understood, and a few hypotheses have arisen concerning these doable mechanisms.

 

On this overview, we focus on the position of particular ESP from the carcinogenic helminths Clonorchis sinensis, Opisthorchis viverrini and Schistosoma haematobium in inducing power irritation and most cancers of their host’s tissues. The parasitic worms Taenia solium, Echinococcus granulosus, Heterakis gallinarum, Trichuris muris and Strongyloides stercoralis, which have less-characterized mechanisms of most cancers induction, are additionally analyzed. Based mostly on the pathological findings in spirocercosis and the mechanisms by which different parasitic helminths induce most cancers, we suggest that the sustained inflammatory response within the canine´s tissues produced in response to the discharge of Sl-ESP homologous to these of different carcinogenic worms could result in the malignant course of in contaminated canine.

 

Spirocerca lupi is a parasitic nematode of canids that induces a myriad of medical manifestations in its host and, in 25% of infections, results in the formation of sarcomas. The outline of the protein composition of the excretory and secretory merchandise (Sl-ESP) of S. lupi has make clear its doable interactions with the host atmosphere, together with migration throughout the host and mechanisms of immunomodulation. Regardless of this, the method by which S. lupi induces most cancers within the canine stays poorly understood, and a few hypotheses have arisen concerning these doable mechanisms. On this overview, we focus on the position of particular ESP from the carcinogenic helminths Clonorchis sinensis, Opisthorchis viverrini and Schistosoma haematobium in inducing power irritation and most cancers of their host’s tissues.

 

The parasitic worms Taenia solium, Echinococcus granulosus, Heterakis gallinarum, Trichuris muris and Strongyloides stercoralis, which have less-characterized mechanisms of most cancers induction, are additionally analyzed. Based mostly on the pathological findings in spirocercosis and the mechanisms by which different parasitic helminths induce most cancers, we suggest that the sustained inflammatory response within the canine´s tissues produced in response to the discharge of Sl-ESP homologous to these of different carcinogenic worms could result in the malignant course of in contaminated canine.

 

iTRAQ-facilitated proteomic evaluation of Bacillus cereus by way of degradation of malachite inexperienced

The extensive use of malachite inexperienced (MG) as a dye has triggered substantial concern owing to its toxicity. Bacillus cereus can towards the poisonous impact of MG and effectively decolourise it. Nonetheless, detailed info concerning its underlying adaptation and degradation mechanisms primarily based on proteomic knowledge is scarce. On this examine, the isobaric tags for relative and absolute quantitation (iTRAQ)-facilitated quantitative technique was utilized to analyse the molecular mechanisms by which B. cereus degrades MG. Based mostly on this evaluation, 209 upregulated proteins and 198 downregulated proteins have been recognized with a false discovery fee of 1% or much less throughout MG biodegradation.
Gene ontology and KEGG evaluation decided that the differentially expressed proteins have been enriched in metabolic processes, catalytic exercise, antioxidant exercise, and responses to stimuli. Moreover, real-time qPCR was utilised to additional verify the regulated proteins concerned in benzoate degradation. The proteins BCE_4076, BCE_5143, BCE_5144, BCE_4651, and BCE_5474 concerned within the benzoate degradation pathway could play an necessary position within the biodegradation of MG by B. cereus. The outcomes of this examine not solely present a complete view of proteomic modifications in B. cereus upon MG loading but additionally make clear the mechanism underlying MG biodegradation by B. cereus.
Spirocerca lupi Proteomics and Its Role in Cancer Development: An Overview of Spirocercosis-Induced Sarcomas and Revision of Helminth-Induced Carcinomas

Integrative proteomics and metabolomics profiling of the protecting results of Phascolosoma esculent ferritin on BMSCs in Cd(II) damage

Ferritin is the foremost intracellular iron storage protein and is important for iron homeostasis and cleansing. Cadmium impacts mobile homeostasis and induces cell toxicity by way of refined mechanisms. Right here, we aimed to discover the mechanisms of cytoprotective impact of Phascolosoma esculenta ferritin (PeFer) on Cd(II)-induced bone marrow mesenchymal stem cell (BMSC) damage. Herein, the consequences of various handled teams on apoptosis and cell cycle have been assessed utilizing circulation cytometric evaluation.
We additional investigated the alterations of the three teams utilizing integrative 2-DE-based proteomics and 1H NMR-based metabolomics profiles. The outcomes point out that PeFer reduces BMSC apoptosis induced by Cd(II) and delays G0/G1 cell cycle development. A complete of 19 proteins and 70 metabolites have been considerably completely different amongst BMSC samples of the three teams.

Magnetic Beads

TRI-C86M05S 100mL
EUR 844.2

Protein A Magnetic Beads

6507-1 each
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Protein G Magnetic Beads

6517-1 each
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Protein L Magnetic Beads

6537-1 each
EUR 352.8

Protein A Magnetic Beads

HY-K0203 1 mL
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Protein G Magnetic Beads

HY-K0204 5 mL
EUR 445.2

Protein A Magnetic beads

EA-IP-015M 1mL
EUR 105
Description: Primary Antibodies

Protein G Magnetic beads

EA-IP-016M 1mL
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Description: Primary Antibodies

Protein L Magnetic beads

EA-IP-017M 1mL
EUR 105
Description: Primary Antibodies

Magnetic Beads (RNA)

AG0104 5 ml, 60 ml Ask for price
Description: The Magnetic Beads (RNA)</strong> are automated for highly efficient RNA purification by specific adsorption.

Protein A/G Magnetic Beads

6527-1 each
EUR 352.8

Protein A/G Magnetic Beads

HY-K0202 1 mL
EUR 157.2

Protein A/G Magnetic Beads

EA-IP-007M 1mL
EUR 80
Description: Primary Antibodies

96 Magnetic Stand (For Magnetic Beads DNA/RNA Extraction/Magnetic Beads DNA/RNA Extraction)

MNS096-W each
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Streptavidin Magnetic Beads

HY-K0208 5 mL
EUR 645.6

Streptavidin Magnetic beads

EA-IP-011M 1mL
EUR 241
Description: Primary Antibodies

Streptavidin Magnetic Beads

CSB001 15 μl
EUR 61

Anti-HA magnetic beads

B26201 1 mL
EUR 579.6
Description: Anti-HA magnetic beads kit is based on hydroxyl magnetic beads covalently coupling with high quality mouse IgG2b monoclonal antibody, used for co-immunoprecipitation and protein purification.

Anti-HA magnetic beads

B26202 5 mL
EUR 1742.4
Description: Anti-HA magnetic beads kit is based on hydroxyl magnetic beads covalently coupling with high quality mouse IgG2b monoclonal antibody, used for co-immunoprecipitation and protein purification.

Anti-HA Magnetic Beads

HY-K0201 1 mL
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SILICA MAGNETIC BEADS 1L

L5011001 1 liter
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Protein A/G/L Magnetic Beads

6547-1 each
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Anti-Myc magnetic beads

B26301 1 mL
EUR 579.6
Description: Anti-Myc magnetic beads kit is based on hydroxyl magnetic beads covalently coupling with mouse IgG1 monoclonal antibody.it is recommended to use for co-immunoprecipitation and protein purification.

Anti-Myc magnetic beads

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EUR 1742.4
Description: Anti-Myc magnetic beads kit is based on hydroxyl magnetic beads covalently coupling with mouse IgG1 monoclonal antibody.it is recommended to use for co-immunoprecipitation and protein purification.

Anti-Flag magnetic beads

B26101 1 mL
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Description: Anti-Flag magnetic beads is based on hydroxyl magnetic beads covalently coupling with mouse IgG1 monoclonal antibody. It is recommended to use for co-immunoprecipitation and protein purification.

Anti-Flag magnetic beads

B26102 5 mL
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Description: Anti-Flag magnetic beads is based on hydroxyl magnetic beads covalently coupling with mouse IgG1 monoclonal antibody. It is recommended to use for co-immunoprecipitation and protein purification.

DNA Cleanup Magnetic Beads

AG0311L 5 ml, 60 ml Ask for price
Description: DNA Cleanup Magnetic Beads are superparamagnetic, non-aggregating iron oxide particles (or ‘microspheres’) which can bind DNA ant high capcity. The highly efficient DNA purification magnetic beads are based clean-up system for the purification of DNA for NGS workflows. Superior yield, purity, and quality over the leading competitors, all at a better value, because we design and manufacture them in-house. DNA Cleanup Magnetic Beads enables faster binding kinetics, with high sensitivity & selectivity, in both manual and automated biomedical and research applications. The purified DNA is of high yield and integrity and is free of inhibitors, ready for use in a number of downstream applications including PCR, qPCR, mutation screening, microarray analysis, sequencing, single nucleotide polymorphism (SNP) and short-tandem repeat (STR) genotyping.

Anti-Flag Magnetic Beads

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SILICA MAGNETIC BEADS 10ML

L5011010 10 ml
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BlackPearl® (Magnetic Beads)

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BlackPearl® (Magnetic Beads)

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Magnetic Beads (DNA) 30 mL

P920-30 30 mL
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Magnetic Beads (DNA) 450 mL

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Magnetic Beads (DNA) 5 mL

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Magnetic Beads (DNA) 60 mL

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Concanavalin A Magnetic Beads

K1308-1 1ml
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Description: Protein & Immunology|Protein Purification and isolation

Concanavalin A Magnetic Beads

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Description: Protein & Immunology|Protein Purification and isolation

Magnetic Beads™ Streptavidin

SMB-B01 5mg
EUR 149.8
Description: The Streptavidin-Magnetic Beads are 2.8 µm superparamagnetic particles covalently coupled to a highly pure form of streptavidin (SA). The beads can be used to capture the biotinylated proteins or other molecules, because Streptavidin (SA) has an extraordinarily high affinity for biotin with a dissociation constant (Kd) on the order of 10−14 mol/L, the Biotinylated molecules can bind to the SA irreversibly.Streptavidin is a tetrameric protein purified from the bacterium Streptomyces avidin, and exhibits high binding affinity for biotin. Able to bind one molecule of biotin with each subunit. Streptavidin (PI=6.0-7.5) has lower level of non-specific binding to various biological components at physiological pH than avidin (PI=7.4), resulting from its isoelectric point (PI).The Streptavidin-Magnetic Beads is easy to capture the biotinylated proteins or other molecules in Chemiluminescence procedures, and the bounded protein have no activity lost, this ready to use products could greatly save your protein coupling time and hassle, and help us get the best performance and highly reproducible results.

Concanavalin A Magnetic beads

EA-IP-014M 1mL
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Description: Primary Antibodies

IP/CoIP Kit (Magnetic Beads)

EA-IP-K007M 50T
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Description: Antibody Application Reagents

Protein A/G Magnetic Beads for IP

B23201 1 ml
EUR 158.4
Description: Protein A/G Magnetic Beads for immunoprecipitation (IP) are based on a biological nanosurface technology (S-TEC). Protein A/G coats the surface of super paramagnetic microspheres with high coating density up to 9.3 × 10^13 molecules/cm2. Compared to similar immune magnetic beads, our Protein A/G beads display much more antibody binding sites therefore using less magnetic beads per reaction and ultimately achiving greater cost-efficiency. Non-specific binding is reduced to an absolute low eliminating any detectable interference with your IP assays. The large, specific surface area of the beads greatly shortens the adsorption time and achieves complete antibody/antigen adsorption process in 10 minutes and complete total purification and precipitation in just 30 minutes. This product can be used on a wide variety of samples, such as in cell lysates, supernatants collected from cell secretion, serum, ascites, and other immune antigens.

Protein A/G Magnetic Beads for IP

B23202 5 ml
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Description: Protein A/G Magnetic Beads for immunoprecipitation (IP) are based on a biological nanosurface technology (S-TEC). Protein A/G coats the surface of super paramagnetic microspheres with high coating density up to 9.3 × 10^13 molecules/cm2. Compared to similar immune magnetic beads, our Protein A/G beads display much more antibody binding sites therefore using less magnetic beads per reaction and ultimately achiving greater cost-efficiency. Non-specific binding is reduced to an absolute low eliminating any detectable interference with your IP assays. The large, specific surface area of the beads greatly shortens the adsorption time and achieves complete antibody/antigen adsorption process in 10 minutes and complete total purification and precipitation in just 30 minutes. This product can be used on a wide variety of samples, such as in cell lysates, supernatants collected from cell secretion, serum, ascites, and other immune antigens.

Protein A BlackPearl® (Magnetic Beads)

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Protein A BlackPearl® (Magnetic Beads)

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Protein A BlackPearl® (Magnetic Beads)

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Protein G BlackPearl® (Magnetic Beads)

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Protein G BlackPearl® (Magnetic Beads)

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Anti-c-Myc Magnetic Beads

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Anti-tGFP magnetic beads, 1ml

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Anti-tGFP magnetic beads, 5ml

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9E10, Anti-Myc Magnetic beads

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9E10, Anti-Myc Magnetic beads

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Magnetic Beads PCR Cleanup Kit

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Magnetic Beads PCR Cleanup Kit

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Magnetic Beads PCR Cleanup Kit

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Anti-HA (Nanobody) Magnetic Beads

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Anti-GFP (Nanobody) Magnetic Beads

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Anti-Myc (Nanobody) Magnetic Beads

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Human FAP-coupled Magnetic Beads

MBS-K077 10mg
EUR 882.9
Description: The biotinylated FAP protein was conjugated to streptavidin magnetic beads. This pre-coupled magnetic bead product can capture the anti-FAP antibody from various assay systems. The beads are in uniform size, narrow size distribution with large surface area and unique surface coating, which can help you get the best performance and highly reproducible results. This FAP coupled magnetic beads will bring great convenience with minimum non-specific binding and developed protocols. This ready-to-use product could greatly save your time and hassle.

Anti-GFP (Nanobody) Magnetic Beads

MBS9143967-INQUIRE INQUIRE Ask for price

Anti-GFP (Nanobody) Magnetic Beads

E45R13193N 500 ul
EUR 570.75

Human CD19-coupled Magnetic Beads

MBS-K005-10mg 10mg
EUR 4392.7
Description: Human CD19 protein is expressed from human 293 cells (HEK293). It contains AA Pro 20 - Lys 291(Accession # P15391-1).

Human CD19-coupled Magnetic Beads

MBS-K005-2mg 2mg
EUR 1427.9
Description: Human CD19 protein is expressed from human 293 cells (HEK293). It contains AA Pro 20 - Lys 291(Accession # P15391-1).

Human CD33-coupled Magnetic Beads

MBC-K008 2mg
EUR 2707.1
Description: Human CD33 protein is expressed from human 293 cells (HEK293). It contains AA Asp 18 - His 259(Accession # P20138-1(R69G)).

Human CD38-coupled Magnetic Beads

MBC-K010 2mg
EUR 2707.1
Description: Human CD38 protein is expressed from human 293 cells (HEK293). It contains AA Val 43 - Ile 300(Accession # P28907-1).

Human EGFR-coupled Magnetic Beads

MBE-K012 2mg
EUR 2707.1
Description: Human EGFR protein is expressed from human 293 cells (HEK293). It contains AA Leu 25 - Ser 645(Accession # P00533-1).

Human PSMA-coupled Magnetic Beads

MBP-K007 2mg
EUR 3349.1
Description: Human PSMA protein is expressed from human 293 cells (HEK293). It contains AA Lys 44 - Ala 750(Accession # Q04609-1).

Human ROR1-coupled Magnetic Beads

MBR-K009 2mg
EUR 2707.1
Description: Human ROR1 protein is expressed from human 293 cells (HEK293). It contains AA Gln 30 - Glu 403(Accession # Q01973-1).

Human BCMA-coupled Magnetic Beads

MBS-K004 2mg
EUR 2707.1
Description: Human BCMA protein is expressed from human 293 cells (HEK293). It contains AA Met 1 - Ala 54(Accession # Q02223-1).

Human CD19-coupled Magnetic Beads

MBS-K005 2mg
EUR 4312.1
Description: Human CD19 protein is expressed from human 293 cells (HEK293). It contains AA Pro 20 - Lys 291(Accession # P15391-1).

Human HER2-coupled Magnetic Beads

MBS-K006 500ug
EUR 2835.5
Description: Human HER2 protein is expressed from human 293 cells (HEK293). It contains AA Thr 23 - Thr 652(Accession # P04626-1).

Human ACE2-coupled Magnetic Beads

MBS-K013 2mg
EUR 2707.1
Description: Human ACE2 protein is expressed from human 293 cells (HEK293). It contains AA Gln 18 - Ser 740(Accession # Q9BYF1-1).

Human CD73-coupled Magnetic Beads

MBS-K022 2mg
EUR 3349.1
Description: Human CD73 Protein is expressed from human 293 cells (HEK293). It contains AA Trp 27 - Ser 549(Accession # P21589-1).

Human CD47-coupled Magnetic Beads

MBS-K023 2mg
EUR 2707.1
Description: Human CD47 Protein is expressed from human 293 cells (HEK293). It contains AA Gln 19 - Pro 139(Accession # Q08722).

Human CD3E-coupled Magnetic Beads

MBS-K026 2mg
EUR 2707.1
Description: Human CD3E Protein is expressed from human 293 cells (HEK293). It contains AA Asp 23 - Asp 126(Accession # P07766-1).

Human CD22-coupled Magnetic Beads

MBS-K052 2mg
EUR 4312.1
Description: Human CD22 Protein is expressed from human 293 cells (HEK293). It contains AA Asp 20 - Arg 687(Accession # P20273-1).

Human DLL3-coupled Magnetic Beads

MBS-K053 2mg
EUR 2707.1
Description: Delta-like protein 3 (DLL3) is a transmembrane protein that belongs to the Delta/Serrate/Lag-2 (DSL) family of Notch ligands.May be required to divert neurons along a specific differentiation pathway. Plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm. DLL3 protein is expressed on the surface of tumor cells but not in normal adult tissues.

Human uPAR-coupled Magnetic Beads

MBS-K076 2mg
EUR 2707.1
Description: Tumors are the result of uncontrolled proliferation of cells in different organs. Tumor development is a multistage process, that includes the generation of primary tumors, separation of tumors from primary sites, degradation of extracellular matrix (ECM), and distant metastasis of tumors. A variety of genes play important roles in the development of tumors, including the cell surface receptor urokinase-type plasminogen activator receptor (uPAR). uPAR is highly expressed in a variety of tumor cells, and a variety of signals regulated by uPAR play significant roles in tumor cell proliferation and metastasis, tumor-related glycolysis, the tumor microenvironment and angiogenesis. Studies have found that some specific drugs and antibodies have unique inhibitory effects on uPAR.

Magnetic Beads for DNA Purification

M1502-5 5 ml
EUR 332.4

DDDDK-Tag Antibody (Magnetic Beads)

abx005594-100l 100 µl
EUR 250

Amylose BlackPearl® (Magnetic Beads)

20161009-1 - Ask for price

Amylose BlackPearl® (Magnetic Beads)

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Human PCSK9-coupled Magnetic Beads

MBS-K054 2mg
EUR 2707.1
Description: Proprotein convertase subtilisin/kexin type 9 (PCSK9) is also known as NARC1 (neural apoptosis regulated convertase), is a newly identified subtilase belonging to the peptidase S8 subfamily. Mouse PCSK9 is synthesized as a soluble zymogen, and undergoes autocatalytic intramolecular processing in the endoplasmic reticulum, resulting in the cleavage of its propeptide that remains associated with the secreted active enzyme with a broad alkaline pH optimum. This protein plays a major regulatory role in cholesterol homeostasis. PCSK9 binds to the epidermal growth factor-like repeat A (EGF-A) domain of the low-density lipoprotein receptor (LDLR), inducing LDLR degradation. PCSK9 may also have a role in the differentiation of cortical neurons. Mutations in this gene have been associated with a rare form of autosomal dominant familial hypercholesterolemia (HCHOLA3).

Human ASGR1-coupled Magnetic Beads

MBS-K055 2mg
EUR 2707.1
Description: ASGPR, a transmembrane C-type lectin, recognizes a wide variety of ligands that contain either terminal galactose (Gal) or N-acetylgalactosamine (GalNAc) residues and has been identified as a highly selective receptor on hepatocytes. The ASGR is composed of both a major (ASGR1) and minor subunit (ASGR2). ASGR1 has been shown to be efficiently targeted to the plasma membrane and to undergo constitutive endocytosis and recycling and found mainly expressed in the human liver.

Human ANGPT2-coupled Magnetic Beads

MBS-K035 2mg
EUR 2707.1
Description: Human ANGPT2 Protein is expressed from human 293 cells (HEK293). It contains AA Lys 275 - Phe 496(Accession # O15123-1).

Human VEGF165-coupled Magnetic Beads

MBS-K036 2mg
EUR 2707.1
Description: Human VEGF165 Protein is expressed from human 293 cells (HEK293). It contains AA Ala 27 - Arg 191(Accession # P15692-4).

Human EGFRvIII-coupled Magnetic Beads

MBS-K020 2mg
EUR 2707.1
Description: Human EGFRvIII Protein is expressed from human 293 cells (HEK293). It contains AA Leu 25- Ser 378(Accession # NP_001333870.1).

Ni-NTA Magnetic Agarose Beads

20-512M1 2ml/Unit
EUR 116.39
Description: Suspension, 5% Magnetic Resin

Ni-NTA Magnetic Agarose Beads

20-512M2 5ml/Unit
EUR 263.6
Description: Suspension, 5% Magnetic Resin

Ni-NTA Magnetic Agarose Beads

20-512M3 10ml/Unit
EUR 477.13
Description: Suspension, 5% Magnetic Resin

Streptavidin BlackPearl® (Magnetic Beads)

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Streptavidin BlackPearl® (Magnetic Beads)

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Human Mesothelin-coupled Magnetic Beads

MBS-K024 2mg
EUR 2707.1
Description: Human Mesothelin Protein is expressed from human 293 cells (HEK293). It contains AA Glu 296 - Gly 580(Accession # Q13421-3(R309P)).

Human HGF R-coupled Magnetic Beads

MBS-K021 2mg
EUR 2707.1
Description: Human HGF R Protein is expressed from human 293 cells (HEK293). It contains AA Glu 25 - Thr 932(Accession # P08581).

Magnetic Beads for DNA size selection

AG0103 5 ml, 60 ml Ask for price
Description: The Magnetic Beads are ideal for DNA purification, concentration and size selection, along with next-generation sequencing library preparation kits.

Human CTLA-4 coupled Magnetic Beads

MBS-K042 2mg
EUR 2707.1
Description: Human CTLA-4 Protein is expressed from human 293 cells (HEK293). It contains AA Ala 37 - Phe 162(Accession # Q6GR94-1).

VAHTS Concanavalin A-coated Magnetic Beads Pro

N515-01-250ul 250 μl
EUR 38.7

VAHTS Concanavalin A-coated Magnetic Beads Pro

N515-02-1ml 1 ml
EUR 129.71

VAHTS Concanavalin A-coated Magnetic Beads Pro

N515-03-5ml 5 ml
EUR 610.95

Magnetic Beads DNA Extraction Kit (Food)

MF004 each
EUR 3

Magnetic Beads DNA Extraction Kit (Food)

MF048 each
EUR 55

Magnetic Beads DNA Extraction Kit (Food)

MF096 each
EUR 99

Nickel (Ni2+) BlackPearl® (Magnetic Beads)

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Nickel (Ni2+) BlackPearl® (Magnetic Beads)

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Human TROP-2-coupled Magnetic Beads

MBS-K028 2mg
EUR 2707.1
Description: Human TROP-2 Protein is expressed from human 293 cells (HEK293). It contains AA Gln 31 - Thr 274(Accession # P09758-1).

Magnetic Beads DNA Extraction Kit (Blood)

MB004 each
EUR 3

Magnetic Beads DNA Extraction Kit (Blood)

MB048 each
EUR 40

Magnetic Beads DNA Extraction Kit (Blood)

MB096 each
EUR 75

Magnetic Beads DNA Extraction Kit (Plant)

MP004 each
EUR 3

Magnetic Beads DNA Extraction Kit (Plant)

MP048 each
EUR 55

Magnetic Beads DNA Extraction Kit (Plant)

MP096 each
EUR 99

Magnetic Beads Micro gDNA Extraction Kit

MM004 each
EUR 3

Magnetic Beads Micro gDNA Extraction Kit

MM048 each
EUR 63

Magnetic Beads Micro gDNA Extraction Kit

MM096 each
EUR 113

Anti-mCherry (Nanobody) Magnetic Beads Ab

AE094 1000μL
EUR 213.2

Human Nectin-4-coupled Magnetic Beads

MBS-K039 2mg
EUR 2707.1
Description: Human Nectin-4 Protein is expressed from human 293 cells (HEK293). It contains AA Gly 32 - Ser 349(Accession # Q96NY8-1).

Magnetic Beads DNA Extraction Kit (Bacteria)

ME004 each
EUR 3

Magnetic Beads DNA Extraction Kit (Bacteria)

ME048 each
EUR 60

Magnetic Beads DNA Extraction Kit (Bacteria)

ME096 each
EUR 110

Calmodulin (CAM) BlackPearl® (Magnetic Beads)

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Calmodulin (CAM) BlackPearl® (Magnetic Beads)

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Calmodulin (CAM) BlackPearl® (Magnetic Beads)

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Glutathione (GSH) BlackPearl® (Magnetic Beads)

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Glutathione (GSH) BlackPearl® (Magnetic Beads)

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Glutathione (GSH) BlackPearl® (Magnetic Beads)

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Human B7-H3(4Ig)-coupled Magnetic Beads

MBS-K040 2mg
EUR 2707.1
Description: Human B7-H3 Protein is expressed from human 293 cells (HEK293). It contains AA Gly 27 - Thr 461(Accession # Q5ZPR3-1).

Mouse monoclonal eRFP antibody, Magnetic beads

TA183034 1 ml Ask for price

Mouse monoclonal eCFP antibody, Magnetic beads

TA183036 1 ml Ask for price

Mouse monoclonal mRFP antibody, Magnetic beads

TA183041 1 ml Ask for price

Mouse monoclonal mRFP antibody, Magnetic beads

TA183042 1 ml Ask for price

Mouse monoclonal mRFP antibody, Magnetic beads

TA183043 1 ml Ask for price

Mouse monoclonal mPlum antibody, Magnetic beads

TA183037 1 ml Ask for price
Notably, multiomics evaluation revealed that Cd(II) may perturb the ER stress-mediated apoptosis pathway and disrupt organic processes associated to the TCA cycle, amino acid metabolism, purine and pyrimidine metabolism, thereby suppressing the cell development fee and initiating apoptosis; nevertheless, the addition of PeFer may shield BMSCs towards cell apoptosis to enhance cell survival by enhancing vitality metabolism. This examine gives a greater understanding of the underlying molecular mechanisms of the protecting impact of PeFer in BMSCs towards Cd(II) damage.

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