Human periodontal ligament stem cells (hPDLSCs) are best seed cells for periodontal regeneration. A larger understanding of the dynamic protein profiles throughout osteogenic differentiation contributed to the advance of periodontal regeneration tissue engineering.
Tandem Mass Tag quantitative proteomics was utilized to disclose the temporal protein expression sample throughout osteogenic differentiation of hPDLSCs on days 0, 3, 7 and 14. Differentially expressed proteins (DEPs) had been clustered and practical annotated by Gene Ontology (GO) phrases. Pathway enrichment evaluation was carried out based mostly on the Kyoto Encyclopedia of Genes and Genomes database, adopted by the anticipated activation utilizing Ingenuity Pathway Evaluation software program. Interplay networks of redox-sensitive signalling pathways and oxidative phosphorylation (OXPHOS) had been performed and the hub protein SOD2 was validated with western blotting.
A complete of 1024 DEPs had been recognized and clustered in 5 distinctive clusters representing dynamic tendencies. The GO enrichment outcomes indicated that proteins with completely different tendencies present completely different capabilities. Pathway enrichment evaluation discovered that OXPHOS was considerably concerned, which additional predicted steady activation. Redox-sensitive signalling pathways with dynamic activation standing confirmed associations with OXPHOS to numerous levels, particularly the sirtuin signalling pathway. SOD2, an necessary element of the sirtuin pathway, shows a persistent improve throughout osteogenesis. Information can be found through ProteomeXchange with identifier PXD020908.
That is the primary in-depth dynamic proteomic evaluation of osteogenic differentiation of hPDLSCs. It demonstrated a dynamic regulatory mechanism of hPDLSC osteogenesis and would possibly present a brand new perspective for analysis on periodontal regeneration.
A proteomic glimpse into the impact of antimalarial medicine on Plasmodium falciparum proteome in the direction of highlighting doable therapeutic targets
There is no such thing as a efficient vaccine in opposition to malaria; subsequently, chemotherapy is thus far the one option to struggle in opposition to this infectious illness. Nevertheless, there’s rising evidences of drug-resistance mechanisms in malaria therapies. Subsequently, the identification of recent drug targets is an pressing want for the medical administration of the illness. Proteomic approaches provide the prospect of figuring out the results of antimalarial medicine on the proteome of Plasmodium parasites. Accordingly, we reviewed the results of antimalarial medicine on the Plasmodium falciparum proteome declaring the relevance of a number of proteins as doable drug targets in malaria therapy. As well as, a number of the P. falciparum stage-specific altered proteins and parasite-host interactions would possibly play necessary roles in pathogenicity, survival, invasion and metabolic pathways and thus function potential sources of drug targets.
On this evaluation, we’ve recognized a number of proteins, together with thioredoxin reductase, helicases, peptidyl-prolyl cis-trans isomerase, endoplasmic reticulum-resident calcium-binding protein, choline/ethanolamine phosphotransferase, purine nucleoside phosphorylase, apical membrane antigen 1, glutamate dehydrogenase, hypoxanthine guanine phosphoribosyl transferase, warmth shock protein 70x, knob-associated histidine-rich protein and erythrocyte membrane protein 1, as promising antimalarial medicine targets. General, proteomic approaches are in a position to partially facilitate discovering doable drug targets. Nevertheless, the mixing of different ‘omics’ and particular pharmaceutical methods with proteomics could improve the therapeutic properties of the important proteins recognized within the P. falciparum proteome.
All however 13 mammalian mitochondrial proteins are encoded by the nuclear genome, translated within the cytosol after which imported into the mitochondria. For a big proportion of the mitochondrial proteins, import is coupled with the cleavage of a presequence known as the transit peptide, and the formation of a brand new N-terminus. Willpower of the neo N-termini has been investigated by proteomic approaches in a number of techniques, however usually in a static solution to compile as many N-termini as doable. Within the current research, we’ve investigated how the mitochondrial proteome and N-terminome react to chemical stimuli that alter mitochondrial metabolism, specifically zinc ions and rapamycin. To this finish, we’ve used a method that analyzes each inside and N-terminal peptides in a single run, the dN-TOP strategy. We used these two very completely different stressors to kind out what might be a generic response to emphasize and what’s particular to every of those stressors.
Assessing technical and organic variation in SWATH-MS-based proteomic evaluation of persistent lymphocytic leukaemia cells
Continual lymphocytic leukaemia (CLL) reveals variable medical course and response to remedy, however the molecular foundation of this variability stays incompletely understood. Information unbiased acquisition (DIA)-MS applied sciences, corresponding to SWATH (Sequential Windowed Acquisition of all THeoretical fragments), present a possibility to check the pathophysiology of CLL on the proteome stage.
Right here, a CLL-specific spectral library (7736 proteins) is described alongside an evaluation of pattern replication and knowledge dealing with necessities for quantitative SWATH-MS evaluation of medical samples. The evaluation was carried out on 6 CLL samples, incorporating organic (IGHV mutational standing), pattern preparation and MS technical replicates. Quantitative data was obtained for 5169 proteins throughout 54 SWATH-MS acquisitions: the sources of variation and completely different computational approaches for batch correction had been assessed.
 Antibody) CD8(C8/468 + C8/144B) Antibody |
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| BNC610750-500 | Biotium | 500uL | EUR 544 |
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Description: Primary antibody against CD8(C8/468 + C8/144B), CF660R conjugate, Concentration: 0.1mg/mL |
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CD8(C8/468 + C8/144B) Antibody |
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| BNC400750-100 | Biotium | 100uL | EUR 199 |
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Description: Primary antibody against CD8(C8/468 + C8/144B), CF640R conjugate, Concentration: 0.1mg/mL |
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CD8(C8/468 + C8/144B) Antibody |
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| BNC400750-500 | Biotium | 500uL | EUR 544 |
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Description: Primary antibody against CD8(C8/468 + C8/144B), CF640R conjugate, Concentration: 0.1mg/mL |
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CD8(C8/468 + C8/144B) Antibody |
|||
| BNC430750-100 | Biotium | 100uL | EUR 199 |
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Description: Primary antibody against CD8(C8/468 + C8/144B), CF543 conjugate, Concentration: 0.1mg/mL |
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CD8(C8/468 + C8/144B) Antibody |
|||
| BNC430750-500 | Biotium | 500uL | EUR 544 |
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Description: Primary antibody against CD8(C8/468 + C8/144B), CF543 conjugate, Concentration: 0.1mg/mL |
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CD8(C8/468 + C8/144B) Antibody |
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| BNC470750-100 | Biotium | 100uL | EUR 199 |
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Description: Primary antibody against CD8(C8/468 + C8/144B), CF647 conjugate, Concentration: 0.1mg/mL |
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CD8(C8/468 + C8/144B) Antibody |
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| BNC470750-500 | Biotium | 500uL | EUR 544 |
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Description: Primary antibody against CD8(C8/468 + C8/144B), CF647 conjugate, Concentration: 0.1mg/mL |
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CD8(C8/468 + C8/144B) Antibody |
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| BNC550750-100 | Biotium | 100uL | EUR 199 |
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Description: Primary antibody against CD8(C8/468 + C8/144B), CF555 conjugate, Concentration: 0.1mg/mL |
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CD8(C8/468 + C8/144B) Antibody |
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| BNC550750-500 | Biotium | 500uL | EUR 544 |
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Description: Primary antibody against CD8(C8/468 + C8/144B), CF555 conjugate, Concentration: 0.1mg/mL |
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CD8(C8/468 + C8/144B) Antibody |
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| BNC040750-100 | Biotium | 100uL | EUR 199 |
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Description: Primary antibody against CD8(C8/468 + C8/144B), CF405S conjugate, Concentration: 0.1mg/mL |
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CD8(C8/468 + C8/144B) Antibody |
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| BNC040750-500 | Biotium | 500uL | EUR 544 |
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Description: Primary antibody against CD8(C8/468 + C8/144B), CF405S conjugate, Concentration: 0.1mg/mL |
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CD8(C8/468 + C8/144B) Antibody |
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| BNC050750-100 | Biotium | 100uL | EUR 199 |
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Description: Primary antibody against CD8(C8/468 + C8/144B), CF405M conjugate, Concentration: 0.1mg/mL |
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CD8(C8/468 + C8/144B) Antibody |
|||
| BNC050750-500 | Biotium | 500uL | EUR 544 |
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Description: Primary antibody against CD8(C8/468 + C8/144B), CF405M conjugate, Concentration: 0.1mg/mL |
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CD8(C8/468 + C8/144B) Antibody |
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| BNC680750-100 | Biotium | 100uL | EUR 199 |
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Description: Primary antibody against CD8(C8/468 + C8/144B), CF568 conjugate, Concentration: 0.1mg/mL |
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CD8(C8/468 + C8/144B) Antibody |
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| BNC680750-500 | Biotium | 500uL | EUR 544 |
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Description: Primary antibody against CD8(C8/468 + C8/144B), CF568 conjugate, Concentration: 0.1mg/mL |
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CD8(C8/468 + C8/144B) Antibody |
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| BNUB0750-100 | Biotium | 100uL | EUR 209 |
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Description: Primary antibody against CD8(C8/468 + C8/144B), Concentration: 0.2mg/mL |
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CD8(C8/468 + C8/144B) Antibody |
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| BNUB0750-500 | Biotium | 500uL | EUR 458 |
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Description: Primary antibody against CD8(C8/468 + C8/144B), Concentration: 0.2mg/mL |
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CD8(C8/468 + C8/144B) Antibody |
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| BNUM0750-50 | Biotium | 50uL | EUR 395 |
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Description: Primary antibody against CD8(C8/468 + C8/144B), 1mg/mL |
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CD8(C8/468 + C8/144B) Antibody |
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| BNC700750-100 | Biotium | 100uL | EUR 199 |
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Description: Primary antibody against CD8(C8/468 + C8/144B), CF770 conjugate, Concentration: 0.1mg/mL |
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CD8(C8/468 + C8/144B) Antibody |
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| BNC700750-500 | Biotium | 500uL | EUR 544 |
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Description: Primary antibody against CD8(C8/468 + C8/144B), CF770 conjugate, Concentration: 0.1mg/mL |
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CD8(C8/468 + C8/144B) Antibody |
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| BNC940750-100 | Biotium | 100uL | EUR 199 |
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Description: Primary antibody against CD8(C8/468 + C8/144B), CF594 conjugate, Concentration: 0.1mg/mL |
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CD8(C8/468 + C8/144B) Antibody |
|||
| BNC940750-500 | Biotium | 500uL | EUR 544 |
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Description: Primary antibody against CD8(C8/468 + C8/144B), CF594 conjugate, Concentration: 0.1mg/mL |
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CD8(C8/468 + C8/144B) Antibody |
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| BNCH0750-100 | Biotium | 100uL | EUR 199 |
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Description: Primary antibody against CD8(C8/468 + C8/144B), Horseradish Peroxidase conjugate, Concentration: 0.1mg/mL |
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CD8(C8/468 + C8/144B) Antibody |
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| BNCH0750-500 | Biotium | 500uL | EUR 544 |
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Description: Primary antibody against CD8(C8/468 + C8/144B), Horseradish Peroxidase conjugate, Concentration: 0.1mg/mL |
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CD8(C8/468 + C8/144B) Antibody |
|||
| BNC800750-100 | Biotium | 100uL | EUR 199 |
|
Description: Primary antibody against CD8(C8/468 + C8/144B), CF680 conjugate, Concentration: 0.1mg/mL |
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CD8(C8/468 + C8/144B) Antibody |
|||
| BNC800750-500 | Biotium | 500uL | EUR 544 |
|
Description: Primary antibody against CD8(C8/468 + C8/144B), CF680 conjugate, Concentration: 0.1mg/mL |
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CD8(C8/468 + C8/144B) Antibody |
|||
| BNCP0750-250 | Biotium | 250uL | EUR 383 |
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Description: Primary antibody against CD8(C8/468 + C8/144B), PerCP conjugate, Concentration: 0.1mg/mL |
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CD8(C8/468 + C8/144B) Antibody |
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| BNCR0750-250 | Biotium | 250uL | EUR 383 |
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Description: Primary antibody against CD8(C8/468 + C8/144B), RPE conjugate, Concentration: 0.1mg/mL |
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CD8(C8/468 + C8/144B) Antibody |
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| BNCA0750-250 | Biotium | 250uL | EUR 383 |
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Description: Primary antibody against CD8(C8/468 + C8/144B), APC conjugate, Concentration: 0.1mg/mL |
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CD8(C8/468 + C8/144B) Antibody |
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| BNCAP0750-100 | Biotium | 100uL | EUR 199 |
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Description: Primary antibody against CD8(C8/468 + C8/144B), Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL |
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CD8(C8/468 + C8/144B) Antibody |
|||
| BNCAP0750-500 | Biotium | 500uL | EUR 544 |
|
Description: Primary antibody against CD8(C8/468 + C8/144B), Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL |
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CD8(C8/468 + C8/144B) Antibody |
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| BNCB0750-100 | Biotium | 100uL | EUR 199 |
|
Description: Primary antibody against CD8(C8/468 + C8/144B), Biotin conjugate, Concentration: 0.1mg/mL |
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CD8(C8/468 + C8/144B) Antibody |
|||
| BNCB0750-500 | Biotium | 500uL | EUR 544 |
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Description: Primary antibody against CD8(C8/468 + C8/144B), Biotin conjugate, Concentration: 0.1mg/mL |
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CD8(C8/468 + C8/144B) Antibody |
|||
| BNC880750-100 | Biotium | 100uL | EUR 199 |
|
Description: Primary antibody against CD8(C8/468 + C8/144B), CF488A conjugate, Concentration: 0.1mg/mL |
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CD8(C8/468 + C8/144B) Antibody |
|||
| BNC880750-500 | Biotium | 500uL | EUR 544 |
|
Description: Primary antibody against CD8(C8/468 + C8/144B), CF488A conjugate, Concentration: 0.1mg/mL |
|||
CD8(C8/468 + C8/144B) Antibody |
|||
| BNC810750-100 | Biotium | 100uL | EUR 199 |
|
Description: Primary antibody against CD8(C8/468 + C8/144B), CF680R conjugate, Concentration: 0.1mg/mL |
|||
CD8(C8/468 + C8/144B) Antibody |
|||
| BNC810750-500 | Biotium | 500uL | EUR 544 |
|
Description: Primary antibody against CD8(C8/468 + C8/144B), CF680R conjugate, Concentration: 0.1mg/mL |
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 C8 Ceramide |
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| 20-abx076676 | Abbexa |
|
|
|
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 C8 ? Polyclonal Antibody |
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| ES8518-100ul | ELK Biotech | 100ul | EUR 279 |
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Description: A Rabbit Polyclonal antibody against C8 ? from Human/Rat. This antibody is tested and validated for WB, ELISA, WB, ELISA |
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C8 ? Polyclonal Antibody |
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| ES8518-50ul | ELK Biotech | 50ul | EUR 207 |
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Description: A Rabbit Polyclonal antibody against C8 ? from Human/Rat. This antibody is tested and validated for WB, ELISA, WB, ELISA |
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C8 ? Polyclonal Antibody |
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| ES8864-100ul | ELK Biotech | 100ul | EUR 279 |
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Description: A Rabbit Polyclonal antibody against C8 ? from Human. This antibody is tested and validated for WB, ELISA, WB, ELISA |
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C8 ? Polyclonal Antibody |
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| ES8864-50ul | ELK Biotech | 50ul | EUR 207 |
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Description: A Rabbit Polyclonal antibody against C8 ? from Human. This antibody is tested and validated for WB, ELISA, WB, ELISA |
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 Complement C8 antibody |
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| 20C-CR2038G | Fitzgerald | 1 ml | EUR 187 |
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Description: Goat polyclonal Complement C8 antibody |
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Complement C8 antibody |
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| 20C-CR6024SP | Fitzgerald | 1 ml | EUR 295 |
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Description: Sheep polyclonal Complement C8 antibody |
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 AlbuVoid™ LC-MS On-Bead For Serum Proteomics |
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| AVB-MS05 | Biotech Support Group | 5 preps | EUR 379 |
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Description: Albumin Removal Kit |
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AlbuVoid™ LC-MS On-Bead For Serum Proteomics |
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| AVB-MS10 | Biotech Support Group | 10 preps | EUR 521 |
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Description: Albumin Removal Kit |
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 HemoVoid™ LC-MS On-Bead For Erythrocytes Proteomics |
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| HVB-MS05 | Biotech Support Group | 5 preps | EUR 379 |
|
Description: Hemoglobin Removal Kit |
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HemoVoid™ LC-MS On-Bead For Erythrocytes Proteomics |
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| HVB-MS10 | Biotech Support Group | 10 preps | EUR 521 |
|
Description: Hemoglobin Removal Kit |
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 Anti-CD8A Antibody Clone C8/468 + C8/144B, Unconjugated-100ug |
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| 925-MSM3-P1 | EnQuireBio | 100ug | EUR 428 |
 Antibody) CD8(C8/468) Antibody |
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| BNC610468-100 | Biotium | 100uL | EUR 199 |
|
Description: Primary antibody against CD8(C8/468), CF660R conjugate, Concentration: 0.1mg/mL |
|||
CD8(C8/468) Antibody |
|||
| BNC610468-500 | Biotium | 500uL | EUR 544 |
|
Description: Primary antibody against CD8(C8/468), CF660R conjugate, Concentration: 0.1mg/mL |
|||
 Antibody) CD8(C8/144B) Antibody |
|||
| BNC610749-100 | Biotium | 100uL | EUR 199 |
|
Description: Primary antibody against CD8(C8/144B), CF660R conjugate, Concentration: 0.1mg/mL |
|||
CD8(C8/144B) Antibody |
|||
| BNC610749-500 | Biotium | 500uL | EUR 544 |
|
Description: Primary antibody against CD8(C8/144B), CF660R conjugate, Concentration: 0.1mg/mL |
|||
 Antibody) CD8(C8/1035) Antibody |
|||
| BNC611035-100 | Biotium | 100uL | EUR 199 |
|
Description: Primary antibody against CD8(C8/1035), CF660R conjugate, Concentration: 0.1mg/mL |
|||
CD8(C8/1035) Antibody |
|||
| BNC611035-500 | Biotium | 500uL | EUR 544 |
|
Description: Primary antibody against CD8(C8/1035), CF660R conjugate, Concentration: 0.1mg/mL |
|||
CD8(C8/468) Antibody |
|||
| BNC680468-100 | Biotium | 100uL | EUR 199 |
|
Description: Primary antibody against CD8(C8/468), CF568 conjugate, Concentration: 0.1mg/mL |
|||
CD8(C8/468) Antibody |
|||
| BNC680468-500 | Biotium | 500uL | EUR 544 |
|
Description: Primary antibody against CD8(C8/468), CF568 conjugate, Concentration: 0.1mg/mL |
|||
CD8(C8/468) Antibody |
|||
| BNC400468-100 | Biotium | 100uL | EUR 199 |
|
Description: Primary antibody against CD8(C8/468), CF640R conjugate, Concentration: 0.1mg/mL |
|||
CD8(C8/468) Antibody |
|||
| BNC400468-500 | Biotium | 500uL | EUR 544 |
|
Description: Primary antibody against CD8(C8/468), CF640R conjugate, Concentration: 0.1mg/mL |
|||
CD8(C8/144B) Antibody |
|||
| BNC400749-100 | Biotium | 100uL | EUR 199 |
|
Description: Primary antibody against CD8(C8/144B), CF640R conjugate, Concentration: 0.1mg/mL |
|||
CD8(C8/144B) Antibody |
|||
| BNC400749-500 | Biotium | 500uL | EUR 544 |
|
Description: Primary antibody against CD8(C8/144B), CF640R conjugate, Concentration: 0.1mg/mL |
|||
CD8(C8/1035) Antibody |
|||
| BNC401035-100 | Biotium | 100uL | EUR 199 |
|
Description: Primary antibody against CD8(C8/1035), CF640R conjugate, Concentration: 0.1mg/mL |
|||
CD8(C8/1035) Antibody |
|||
| BNC401035-500 | Biotium | 500uL | EUR 544 |
|
Description: Primary antibody against CD8(C8/1035), CF640R conjugate, Concentration: 0.1mg/mL |
|||
CD8(C8/468) Antibody |
|||
| BNC430468-100 | Biotium | 100uL | EUR 199 |
|
Description: Primary antibody against CD8(C8/468), CF543 conjugate, Concentration: 0.1mg/mL |
|||
CD8(C8/468) Antibody |
|||
| BNC430468-500 | Biotium | 500uL | EUR 544 |
|
Description: Primary antibody against CD8(C8/468), CF543 conjugate, Concentration: 0.1mg/mL |
|||
CD8(C8/144B) Antibody |
|||
| BNC430749-100 | Biotium | 100uL | EUR 199 |
|
Description: Primary antibody against CD8(C8/144B), CF543 conjugate, Concentration: 0.1mg/mL |
|||
CD8(C8/144B) Antibody |
|||
| BNC430749-500 | Biotium | 500uL | EUR 544 |
|
Description: Primary antibody against CD8(C8/144B), CF543 conjugate, Concentration: 0.1mg/mL |
|||
CD8(C8/1035) Antibody |
|||
| BNC431035-100 | Biotium | 100uL | EUR 199 |
|
Description: Primary antibody against CD8(C8/1035), CF543 conjugate, Concentration: 0.1mg/mL |
|||
CD8(C8/1035) Antibody |
|||
| BNC431035-500 | Biotium | 500uL | EUR 544 |
|
Description: Primary antibody against CD8(C8/1035), CF543 conjugate, Concentration: 0.1mg/mL |
|||
CD8(C8/468) Antibody |
|||
| BNC470468-100 | Biotium | 100uL | EUR 199 |
|
Description: Primary antibody against CD8(C8/468), CF647 conjugate, Concentration: 0.1mg/mL |
|||
CD8(C8/468) Antibody |
|||
| BNC470468-500 | Biotium | 500uL | EUR 544 |
|
Description: Primary antibody against CD8(C8/468), CF647 conjugate, Concentration: 0.1mg/mL |
|||
CD8(C8/144B) Antibody |
|||
| BNC470749-100 | Biotium | 100uL | EUR 199 |
|
Description: Primary antibody against CD8(C8/144B), CF647 conjugate, Concentration: 0.1mg/mL |
|||
CD8(C8/144B) Antibody |
|||
| BNC470749-500 | Biotium | 500uL | EUR 544 |
|
Description: Primary antibody against CD8(C8/144B), CF647 conjugate, Concentration: 0.1mg/mL |
|||
CD8(C8/1035) Antibody |
|||
| BNC471035-100 | Biotium | 100uL | EUR 199 |
|
Description: Primary antibody against CD8(C8/1035), CF647 conjugate, Concentration: 0.1mg/mL |
|||
CD8(C8/1035) Antibody |
|||
| BNC471035-500 | Biotium | 500uL | EUR 544 |
|
Description: Primary antibody against CD8(C8/1035), CF647 conjugate, Concentration: 0.1mg/mL |
|||
CD8(C8/468) Antibody |
|||
| BNC550468-100 | Biotium | 100uL | EUR 199 |
|
Description: Primary antibody against CD8(C8/468), CF555 conjugate, Concentration: 0.1mg/mL |
|||
CD8(C8/468) Antibody |
|||
| BNC550468-500 | Biotium | 500uL | EUR 544 |
|
Description: Primary antibody against CD8(C8/468), CF555 conjugate, Concentration: 0.1mg/mL |
|||
CD8(C8/144B) Antibody |
|||
| BNC550749-100 | Biotium | 100uL | EUR 199 |
|
Description: Primary antibody against CD8(C8/144B), CF555 conjugate, Concentration: 0.1mg/mL |
|||
CD8(C8/144B) Antibody |
|||
| BNC550749-500 | Biotium | 500uL | EUR 544 |
|
Description: Primary antibody against CD8(C8/144B), CF555 conjugate, Concentration: 0.1mg/mL |
|||
CD8(C8/1035) Antibody |
|||
| BNC551035-100 | Biotium | 100uL | EUR 199 |
|
Description: Primary antibody against CD8(C8/1035), CF555 conjugate, Concentration: 0.1mg/mL |
|||
CD8(C8/1035) Antibody |
|||
| BNC551035-500 | Biotium | 500uL | EUR 544 |
|
Description: Primary antibody against CD8(C8/1035), CF555 conjugate, Concentration: 0.1mg/mL |
|||
CD8(C8/468) Antibody |
|||
| BNC040468-100 | Biotium | 100uL | EUR 199 |
|
Description: Primary antibody against CD8(C8/468), CF405S conjugate, Concentration: 0.1mg/mL |
|||
CD8(C8/468) Antibody |
|||
| BNC040468-500 | Biotium | 500uL | EUR 544 |
|
Description: Primary antibody against CD8(C8/468), CF405S conjugate, Concentration: 0.1mg/mL |
|||
CD8(C8/144B) Antibody |
|||
| BNC040749-100 | Biotium | 100uL | EUR 199 |
|
Description: Primary antibody against CD8(C8/144B), CF405S conjugate, Concentration: 0.1mg/mL |
|||
CD8(C8/144B) Antibody |
|||
| BNC040749-500 | Biotium | 500uL | EUR 544 |
|
Description: Primary antibody against CD8(C8/144B), CF405S conjugate, Concentration: 0.1mg/mL |
|||
-CP 47,497-C8-homolog) (±)-CP 47,497-C8-homolog |
|||
| B7940-10 | ApexBio | 10 mg | EUR 206 |
(±)-CP 47,497-C8-homolog |
|||
| B7940-25 | ApexBio | 25 mg | EUR 419 |
(±)-CP 47,497-C8-homolog |
|||
| B7940-5 | ApexBio | 5 mg | EUR 132 |
CD8(C8/468) Antibody |
|||
| BNC050468-100 | Biotium | 100uL | EUR 199 |
|
Description: Primary antibody against CD8(C8/468), CF405M conjugate, Concentration: 0.1mg/mL |
|||
CD8(C8/468) Antibody |
|||
| BNC050468-500 | Biotium | 500uL | EUR 544 |
|
Description: Primary antibody against CD8(C8/468), CF405M conjugate, Concentration: 0.1mg/mL |
|||
CD8(C8/144B) Antibody |
|||
| BNC050749-100 | Biotium | 100uL | EUR 199 |
|
Description: Primary antibody against CD8(C8/144B), CF405M conjugate, Concentration: 0.1mg/mL |
|||
CD8(C8/144B) Antibody |
|||
| BNC050749-500 | Biotium | 500uL | EUR 544 |
|
Description: Primary antibody against CD8(C8/144B), CF405M conjugate, Concentration: 0.1mg/mL |
|||
CD8(C8/1035) Antibody |
|||
| BNC051035-100 | Biotium | 100uL | EUR 199 |
|
Description: Primary antibody against CD8(C8/1035), CF405M conjugate, Concentration: 0.1mg/mL |
|||
CD8(C8/1035) Antibody |
|||
| BNC051035-500 | Biotium | 500uL | EUR 544 |
|
Description: Primary antibody against CD8(C8/1035), CF405M conjugate, Concentration: 0.1mg/mL |
|||
CD8(C8/1035) Antibody |
|||
| BNC041035-100 | Biotium | 100uL | EUR 199 |
|
Description: Primary antibody against CD8(C8/1035), CF405S conjugate, Concentration: 0.1mg/mL |
|||
CD8(C8/1035) Antibody |
|||
| BNC041035-500 | Biotium | 500uL | EUR 544 |
|
Description: Primary antibody against CD8(C8/1035), CF405S conjugate, Concentration: 0.1mg/mL |
|||
CD8(C8/144B) Antibody |
|||
| BNC680749-100 | Biotium | 100uL | EUR 199 |
|
Description: Primary antibody against CD8(C8/144B), CF568 conjugate, Concentration: 0.1mg/mL |
|||
CD8(C8/144B) Antibody |
|||
| BNC680749-500 | Biotium | 500uL | EUR 544 |
|
Description: Primary antibody against CD8(C8/144B), CF568 conjugate, Concentration: 0.1mg/mL |
|||
CD8(C8/144B) Antibody |
|||
| BNUB0749-100 | Biotium | 100uL | EUR 209 |
|
Description: Primary antibody against CD8(C8/144B), Concentration: 0.2mg/mL |
|||
CD8(C8/144B) Antibody |
|||
| BNUB0749-500 | Biotium | 500uL | EUR 458 |
|
Description: Primary antibody against CD8(C8/144B), Concentration: 0.2mg/mL |
|||
CD8(C8/1035) Antibody |
|||
| BNUB1035-100 | Biotium | 100uL | EUR 209 |
|
Description: Primary antibody against CD8(C8/1035), Concentration: 0.2mg/mL |
|||
CD8(C8/1035) Antibody |
|||
| BNUB1035-500 | Biotium | 500uL | EUR 458 |
|
Description: Primary antibody against CD8(C8/1035), Concentration: 0.2mg/mL |
|||
CD8(C8/468) Antibody |
|||
| BNUM0468-50 | Biotium | 50uL | EUR 395 |
|
Description: Primary antibody against CD8(C8/468), 1mg/mL |
|||
CD8(C8/144B) Antibody |
|||
| BNUM0749-50 | Biotium | 50uL | EUR 395 |
|
Description: Primary antibody against CD8(C8/144B), 1mg/mL |
|||
CD8(C8/1035) Antibody |
|||
| BNUM1035-50 | Biotium | 50uL | EUR 395 |
|
Description: Primary antibody against CD8(C8/1035), 1mg/mL |
|||
CD8(C8/1035) Antibody |
|||
| BNC681035-100 | Biotium | 100uL | EUR 199 |
|
Description: Primary antibody against CD8(C8/1035), CF568 conjugate, Concentration: 0.1mg/mL |
|||
CD8(C8/1035) Antibody |
|||
| BNC681035-500 | Biotium | 500uL | EUR 544 |
|
Description: Primary antibody against CD8(C8/1035), CF568 conjugate, Concentration: 0.1mg/mL |
|||
CD8(C8/468) Antibody |
|||
| BNC700468-100 | Biotium | 100uL | EUR 199 |
|
Description: Primary antibody against CD8(C8/468), CF770 conjugate, Concentration: 0.1mg/mL |
|||
CD8(C8/468) Antibody |
|||
| BNC700468-500 | Biotium | 500uL | EUR 544 |
|
Description: Primary antibody against CD8(C8/468), CF770 conjugate, Concentration: 0.1mg/mL |
|||
CD8(C8/144B) Antibody |
|||
| BNC700749-100 | Biotium | 100uL | EUR 199 |
|
Description: Primary antibody against CD8(C8/144B), CF770 conjugate, Concentration: 0.1mg/mL |
|||
CD8(C8/144B) Antibody |
|||
| BNC700749-500 | Biotium | 500uL | EUR 544 |
|
Description: Primary antibody against CD8(C8/144B), CF770 conjugate, Concentration: 0.1mg/mL |
|||
CD8(C8/1035) Antibody |
|||
| BNC701035-100 | Biotium | 100uL | EUR 199 |
|
Description: Primary antibody against CD8(C8/1035), CF770 conjugate, Concentration: 0.1mg/mL |
|||
CD8(C8/1035) Antibody |
|||
| BNC701035-500 | Biotium | 500uL | EUR 544 |
|
Description: Primary antibody against CD8(C8/1035), CF770 conjugate, Concentration: 0.1mg/mL |
|||
CD8(C8/468) Antibody |
|||
| BNC940468-100 | Biotium | 100uL | EUR 199 |
|
Description: Primary antibody against CD8(C8/468), CF594 conjugate, Concentration: 0.1mg/mL |
|||
CD8(C8/468) Antibody |
|||
| BNC940468-500 | Biotium | 500uL | EUR 544 |
|
Description: Primary antibody against CD8(C8/468), CF594 conjugate, Concentration: 0.1mg/mL |
|||
CD8(C8/144B) Antibody |
|||
| BNC940749-100 | Biotium | 100uL | EUR 199 |
|
Description: Primary antibody against CD8(C8/144B), CF594 conjugate, Concentration: 0.1mg/mL |
|||
CD8(C8/144B) Antibody |
|||
| BNC940749-500 | Biotium | 500uL | EUR 544 |
|
Description: Primary antibody against CD8(C8/144B), CF594 conjugate, Concentration: 0.1mg/mL |
|||
CD8(C8/1035) Antibody |
|||
| BNC941035-100 | Biotium | 100uL | EUR 199 |
|
Description: Primary antibody against CD8(C8/1035), CF594 conjugate, Concentration: 0.1mg/mL |
|||
CD8(C8/1035) Antibody |
|||
| BNC941035-500 | Biotium | 500uL | EUR 544 |
|
Description: Primary antibody against CD8(C8/1035), CF594 conjugate, Concentration: 0.1mg/mL |
|||
CD8(C8/468) Antibody |
|||
| BNCH0468-100 | Biotium | 100uL | EUR 199 |
|
Description: Primary antibody against CD8(C8/468), Horseradish Peroxidase conjugate, Concentration: 0.1mg/mL |
|||
CD8(C8/468) Antibody |
|||
| BNCH0468-500 | Biotium | 500uL | EUR 544 |
|
Description: Primary antibody against CD8(C8/468), Horseradish Peroxidase conjugate, Concentration: 0.1mg/mL |
|||
CD8(C8/144B) Antibody |
|||
| BNCH0749-100 | Biotium | 100uL | EUR 199 |
|
Description: Primary antibody against CD8(C8/144B), Horseradish Peroxidase conjugate, Concentration: 0.1mg/mL |
|||
CD8(C8/144B) Antibody |
|||
| BNCH0749-500 | Biotium | 500uL | EUR 544 |
|
Description: Primary antibody against CD8(C8/144B), Horseradish Peroxidase conjugate, Concentration: 0.1mg/mL |
|||
CD8(C8/1035) Antibody |
|||
| BNCH1035-100 | Biotium | 100uL | EUR 199 |
|
Description: Primary antibody against CD8(C8/1035), Horseradish Peroxidase conjugate, Concentration: 0.1mg/mL |
|||
CD8(C8/1035) Antibody |
|||
| BNCH1035-500 | Biotium | 500uL | EUR 544 |
|
Description: Primary antibody against CD8(C8/1035), Horseradish Peroxidase conjugate, Concentration: 0.1mg/mL |
|||
CD8(C8/468) Antibody |
|||
| BNC800468-100 | Biotium | 100uL | EUR 199 |
|
Description: Primary antibody against CD8(C8/468), CF680 conjugate, Concentration: 0.1mg/mL |
|||
CD8(C8/468) Antibody |
|||
| BNC800468-500 | Biotium | 500uL | EUR 544 |
|
Description: Primary antibody against CD8(C8/468), CF680 conjugate, Concentration: 0.1mg/mL |
|||
CD8(C8/144B) Antibody |
|||
| BNC800749-100 | Biotium | 100uL | EUR 199 |
|
Description: Primary antibody against CD8(C8/144B), CF680 conjugate, Concentration: 0.1mg/mL |
|||
CD8(C8/144B) Antibody |
|||
| BNC800749-500 | Biotium | 500uL | EUR 544 |
|
Description: Primary antibody against CD8(C8/144B), CF680 conjugate, Concentration: 0.1mg/mL |
|||
CD8(C8/1035) Antibody |
|||
| BNC801035-100 | Biotium | 100uL | EUR 199 |
|
Description: Primary antibody against CD8(C8/1035), CF680 conjugate, Concentration: 0.1mg/mL |
|||
CD8(C8/1035) Antibody |
|||
| BNC801035-500 | Biotium | 500uL | EUR 544 |
|
Description: Primary antibody against CD8(C8/1035), CF680 conjugate, Concentration: 0.1mg/mL |
|||
CD8(C8/468) Antibody |
|||
| BNC810468-100 | Biotium | 100uL | EUR 199 |
|
Description: Primary antibody against CD8(C8/468), CF680R conjugate, Concentration: 0.1mg/mL |
|||
CD8(C8/468) Antibody |
|||
| BNC810468-500 | Biotium | 500uL | EUR 544 |
|
Description: Primary antibody against CD8(C8/468), CF680R conjugate, Concentration: 0.1mg/mL |
|||
CD8(C8/468) Antibody |
|||
| BNCP0468-250 | Biotium | 250uL | EUR 383 |
|
Description: Primary antibody against CD8(C8/468), PerCP conjugate, Concentration: 0.1mg/mL |
|||
CD8(C8/144B) Antibody |
|||
| BNCP0749-250 | Biotium | 250uL | EUR 383 |
|
Description: Primary antibody against CD8(C8/144B), PerCP conjugate, Concentration: 0.1mg/mL |
|||
CD8(C8/1035) Antibody |
|||
| BNCP1035-250 | Biotium | 250uL | EUR 383 |
|
Description: Primary antibody against CD8(C8/1035), PerCP conjugate, Concentration: 0.1mg/mL |
|||
CD8(C8/468) Antibody |
|||
| BNCR0468-250 | Biotium | 250uL | EUR 383 |
|
Description: Primary antibody against CD8(C8/468), RPE conjugate, Concentration: 0.1mg/mL |
|||
CD8(C8/144B) Antibody |
|||
| BNCR0749-250 | Biotium | 250uL | EUR 383 |
|
Description: Primary antibody against CD8(C8/144B), RPE conjugate, Concentration: 0.1mg/mL |
|||
CD8(C8/1035) Antibody |
|||
| BNCR1035-250 | Biotium | 250uL | EUR 383 |
|
Description: Primary antibody against CD8(C8/1035), RPE conjugate, Concentration: 0.1mg/mL |
|||
CD8(C8/468) Antibody |
|||
| BNCA0468-250 | Biotium | 250uL | EUR 383 |
|
Description: Primary antibody against CD8(C8/468), APC conjugate, Concentration: 0.1mg/mL |
|||
CD8(C8/144B) Antibody |
|||
| BNCA0749-250 | Biotium | 250uL | EUR 383 |
|
Description: Primary antibody against CD8(C8/144B), APC conjugate, Concentration: 0.1mg/mL |
|||
CD8(C8/1035) Antibody |
|||
| BNCA1035-250 | Biotium | 250uL | EUR 383 |
|
Description: Primary antibody against CD8(C8/1035), APC conjugate, Concentration: 0.1mg/mL |
|||
CD8(C8/468) Antibody |
|||
| BNCAP0468-100 | Biotium | 100uL | EUR 199 |
|
Description: Primary antibody against CD8(C8/468), Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL |
|||
CD8(C8/468) Antibody |
|||
| BNCAP0468-500 | Biotium | 500uL | EUR 544 |
|
Description: Primary antibody against CD8(C8/468), Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL |
|||
CD8(C8/144B) Antibody |
|||
| BNCAP0749-100 | Biotium | 100uL | EUR 199 |
|
Description: Primary antibody against CD8(C8/144B), Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL |
|||
CD8(C8/144B) Antibody |
|||
| BNCAP0749-500 | Biotium | 500uL | EUR 544 |
|
Description: Primary antibody against CD8(C8/144B), Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL |
|||
CD8(C8/1035) Antibody |
|||
| BNCAP1035-100 | Biotium | 100uL | EUR 199 |
|
Description: Primary antibody against CD8(C8/1035), Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL |
|||
CD8(C8/1035) Antibody |
|||
| BNCAP1035-500 | Biotium | 500uL | EUR 544 |
|
Description: Primary antibody against CD8(C8/1035), Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL |
|||
CD8(C8/468) Antibody |
|||
| BNCB0468-100 | Biotium | 100uL | EUR 199 |
|
Description: Primary antibody against CD8(C8/468), Biotin conjugate, Concentration: 0.1mg/mL |
|||
CD8(C8/468) Antibody |
|||
| BNCB0468-500 | Biotium | 500uL | EUR 544 |
|
Description: Primary antibody against CD8(C8/468), Biotin conjugate, Concentration: 0.1mg/mL |
|||
CD8(C8/144B) Antibody |
|||
| BNCB0749-100 | Biotium | 100uL | EUR 199 |
|
Description: Primary antibody against CD8(C8/144B), Biotin conjugate, Concentration: 0.1mg/mL |
|||
CD8(C8/144B) Antibody |
|||
| BNCB0749-500 | Biotium | 500uL | EUR 544 |
|
Description: Primary antibody against CD8(C8/144B), Biotin conjugate, Concentration: 0.1mg/mL |
|||
Purposeful enrichment evaluation of proteins related to IGHV mutational standing confirmed vital overlap with earlier research based mostly on gene expression profiling. Lastly, an strategy to carry out statistical energy evaluation in proteomics research was applied. This research gives a worthwhile useful resource for researchers engaged on the proteomics of CLL. It additionally establishes a sound framework for the design of sufficiently powered medical proteomics research. Certainly, this research exhibits that it’s doable to derive biologically believable hypotheses from a comparatively small dataset.